The human body is constantly undergoing metabolic processes to sustain life and maintain homeostasis. These processes can be divided into two main states: the absorptive state and the postabsorptive state.
The absorptive state, also known as the fed state, occurs when the body is actively digesting and absorbing nutrients from food. This typically occurs after a meal has been consumed and can last for several hours. During the absorptive state, the body's main energy source is glucose, which is derived from the breakdown of carbohydrates in the diet. Glucose is used by cells throughout the body to produce energy and support various physiological processes.
In contrast, the postabsorptive state, also known as the fasting state, occurs when the body is not actively digesting and absorbing nutrients. This typically occurs between meals or during periods of extended fasting. During the postabsorptive state, the body's main energy source shifts from glucose to fat. The liver breaks down stored glycogen into glucose, which is then released into the bloodstream to be used by cells as an energy source. If glycogen stores become depleted, the body begins to break down fats from fat cells and convert them into molecules called ketones, which can also be used by cells as an energy source.
The absorptive and postabsorptive states have important implications for energy metabolism and overall health. In the absorptive state, the body is able to easily obtain energy from the diet, which can be used to support various physiological processes. However, if the body is constantly in the absorptive state and consuming more calories than it needs, it can lead to weight gain and other negative health outcomes. On the other hand, the postabsorptive state can be beneficial for weight loss and improving overall health, as it forces the body to rely on stored energy sources rather than constantly consuming new nutrients.
In conclusion, the absorptive and postabsorptive states of metabolism refer to the body's use of nutrients and energy sources at different times. Understanding these states can help individuals make informed decisions about their diet and lifestyle to support optimal health.
Metabolic States of the Body · Anatomy and Physiology
Insulin stimulates the uptake of glucose into the cells. After ingestion of food, fats and proteins are processed as described previously; however, the glucose processing changes a bit. Other factors, such as hormones and neurotransmitters, potentiate or inhibit the effects of the blood nutrients on insulin secretion. Evidence has also been reported, which implicates environmental toxins. The absorptive state is the period during which ingested nutrients enter the blood and some of these nutrients supply the energy need of the body while the remainder is stored. Pyruvate, lactate, and alanine from muscle cells are not converted into acetyl CoA and used in the Krebs cycle, but are exported to the liver to be used in the synthesis of glucose.
Absorptive and Postabsorptive States
As the postabsorptive state begins, glucose levels drop, and there is a corresponding drop in insulin levels. Muscle is quantitatively the most important tissue in this respect. If the fast is not broken and starvation begins to set in, during the initial days, glucose produced from gluconeogenesis is still used by the brain and organs. For example, muscles will switch from using glucose to fatty acids as fuel. At the start of exercising the energy the body gets quickly is from the anaerobic metabolism using mostly muscle glycogen.
THE ABSORPTIVE AND POST
The constituent parts of these carbohydrates, fats, and proteins are transported across the intestinal wall and enter the bloodstream sugars and amino acids or the lymphatic system fats. This glucose is released from the liver to be used by the peripheral tissues and the brain. Glucose consumption in the tissues and glucose production are balanced when the body is at rest. The ingestion of food and the rise of glucose concentrations in the bloodstream stimulate pancreatic beta cells to release insulin into the bloodstream, where it initiates the absorption of blood glucose by liver hepatocytes, and by adipose and muscle cells. Digestion begins the moment you put food into your mouth, as the food is broken down into its constituent parts to be absorbed through the intestine. Apart from the symptoms mentioned in the patient above listlessness, weight loss, polyuria, polydipsia, Kussmaul breathing , vomiting and abdominal discomfort, mental confusion and coma, and tachycardia and hypertension can also be present.
metabolsim during absorptive and postabsorptive states Flashcards
Absorptive and Postabsorptive States The absorptive state is the time during and right after eating a meal. Once inside these cells, glucose is immediately converted into glucose-6-phosphate. The doctor noticed that her breathing was rapid and shallow Kussmaul breathing , and that it smelled of acetone. Overall survival is dependent on the amount of fat and protein stored in the body. Blood Glucose Responses and Incidence of Hypoglycemia in Elite Tennis Players. Furthermore, during insulin and partial glucagon deficiency, and the exclusive partial deficiency of glucagon, the rate of glucose appearance increases to a point greater than the rate of glucose disappearance. During this state glucose is the most important energy fuel.
